National Basketball Retired Players Association, Sheryl Swoopes and Flexion Therapeutics Announce Partnership to Raise Awareness of ZILRETTA®
“We are excited to partner with the NBRPA to raise awareness of knee OA and ZILRETTA, and we are truly honored to be working with Sheryl, a world-class athlete who continues to exemplify greatness well after the height of her career,” said
Swoopes, the first player to be signed in the
“The best partnerships are all about authenticity, and we found out through a survey of our membership that knee pain ranked among retired players’ top ailments following their careers,” said
Swoopes added, “I fully understand the way OA knee pain can impact your life in every aspect, not just physically but mentally. To be able to tell my story and share the results of what can be done with treatment with my colleagues, friends, former players and family is very important. This partnership will not only help many of the athletes who have played in the NBA and
Swoopes was treated by
More information on how to find a treating physician can be found at https://www.getthez.com or by calling 888-600-GETZ (4389).
The NBRPA represents over 1,000 former NBA and
Indication and Important Safety Information for ZILRETTA
Indication: ZILRETTA is indicated as an intra-articular injection for the management of OA pain of the knee.
Limitation of Use: The efficacy and safety of repeat administration of ZILRETTA have not been demonstrated.
Contraindication: ZILRETTA is contraindicated in patients who are hypersensitive to triamcinolone acetonide, corticosteroids or any components of the product.
Warnings and Precautions:
- Intra-articular Use Only: ZILRETTA has not been evaluated and should not be administered by epidural, intrathecal, intravenous, intraocular, intramuscular, intradermal, or subcutaneous routes. Serious events have been reported with epidural and intrathecal administration of corticosteroids and none are approved for this use. ZILRETTA should not be considered safe for epidural or intrathecal administration.
- Hypersensitivity Reactions: Rare instances of anaphylaxis, including serious cases, have occurred in patients with hypersensitivity to corticosteroids.
- Joint Infection and Damage: A marked increase in pain accompanied by local swelling, restriction of joint motion, fever, and malaise are suggestive of septic arthritis. Examine joint fluid to exclude a septic process. If diagnosis is confirmed, institute appropriate antimicrobial therapy. Avoid injecting corticosteroids into a previously infected or unstable joint. Intra-articular administration may result in damage to joint tissues.
- Increased Risk of Infections: Infection with any pathogen in any location of the body may be associated with corticosteroid use. Corticosteroids may increase the susceptibility to new infection and decrease resistance and the ability to localize infection.
- Alterations in Endocrine Function: Corticosteroids can produce reversible hypothalamic-pituitary-adrenal axis suppression, with potential for adrenal insufficiency after withdrawal of treatment, which may persist for months. In situations of stress during that period, institute corticosteroid replacement therapy.
- Cardiovascular and Renal Effects: Corticosteroids can cause blood pressure elevation, salt and water retention, and increased potassium excretion. Monitor patients with congestive heart failure, hypertension, and renal insufficiency for edema, weight gain, and electrolyte imbalance. Dietary salt restriction and potassium supplementation may be needed.
- Increased Intraocular Pressure: Corticosteroid use may be associated with increased intraocular pressure. Monitor patients with elevated intraocular pressure for potential treatment adjustment.
- Gastrointestinal Perforation: Corticosteroid administration may increase risk of gastrointestinal perforation in patients with certain GI disorders and fresh intestinal anastomoses. Avoid corticosteroids in these patients.
- Alterations in Bone Density: Corticosteroids decrease bone formation and increase bone resorption. Special consideration should be given to patients with or at increased risk of osteoporosis prior to treatment.
- Behavior and Mood Disturbances: Corticosteroids may cause adverse psychiatric reactions. Prior to treatment, special consideration should be given to patients with previous or current emotional instability or psychiatric illness. Advise patients to immediately report any behavior or mood disturbances.
Adverse Reactions
The most commonly reported adverse reactions (incidence ≥1%) in clinical studies included sinusitis, cough, and contusions.
Please see ZilrettaLabel.com for full Prescribing Information.
About the
About Flexion Therapeutics
About ZILRETTA
On October 6, 2017, ZILRETTA was approved by the U.S. FDA as the first and only extended-release intra-articular therapy for patients confronting OA-related knee pain. ZILRETTA employs proprietary microsphere technology combining triamcinolone acetonide—a commonly administered, short-acting corticosteroid—with a poly lactic-co-glycolic acid (PLGA) matrix to provide extended pain relief. The pivotal Phase 3 trial on which the approval of ZILRETTA was based showed that ZILRETTA significantly reduced OA knee pain for 12 weeks, with some people experiencing pain relief through Week 16. Learn more at www.zilretta.com.
Media Contacts:
NBRPA:
T: 917-566-8345
joefavorito2@gmail.com
T: 516-749-9894
jmanteiga@legendsofbasketball.com
T: 781-305-7194
syoung@flexiontherapeutics.com
T: 781-305-7137
jdowns@flexiontherapeutics.com
Photos accompanying this announcement are available at
https://www.globenewswire.com/NewsRoom/AttachmentNg/bcbf0259-aa32-408d-8a3b-f70b6ea02375
https://www.globenewswire.com/NewsRoom/AttachmentNg/b83cf1fc-c37e-41a5-85ba-f083ed2eef2d
Sheryl Swoopes , WNBA Legend, Basketball Hall of Famer
Flexion Therapeutics partners with the National Basketball Retired Players Association and Sheryl Swoopes to raise awareness of osteoarthritis knee pain. Photo credit NBAE/GETTY Images.
Sheryl Swoopes , WNBA Legend, Basketball Hall of Famer
Flexion Therapeutics partners with the National Basketball Retired Players Association and Sheryl Swoopes to raise awareness of osteoarthritis knee pain. Photo credit NBAE/GETTY Images.
Source: Flexion Therapeutics, Inc.