Ownership Profile

Shareholder Holders Values ($) % O/S Shares
Institution 151 608 103.41 32,811,903
Mutual Fund 157 178 29.08 9,227,487
Shareholder Holders Values Change ($) % O/S Shares Change
Buyers 88 117.72 20.20 6,410,673
Sellers 46 -43.29 7.11 -2,256,231
Net -- 74.42 13.09 4,154,442
Shareholder Values ($) % O/S Shares
Top 10 Inst. 407 70.07 22,234,113
Top 20 Inst. 529.23 90.26 28,641,353
Top 50 Inst. 588.13 100.05 31,745,934
Total Inst. 588.13 100.05 31,745,934
Shareholder Holders Values ($) % O/S Shares
Index 23 80 13.35 4,198,969
CoreGrowth 23 23 3.88 1,221,121
AggresGr 3 10 1.74 547,437
Growth 7 3 0.54 168,802
IncomeValue 1 4 0.61 192,282
Yield 2 1 0.10 30,660
VCPrivateEquity 4 118 22.31 7,019,453
HedgeFund 12 118 19.75 6,213,612
GARP 13 37 6.17 1,939,903
BrokerDealer 18 14 2.28 716,274
Specialty 2 0 0.03 10,408
CoreValue 15 110 18.32 5,765,455
DeepValue 4 35 5.77 1,814,400
Momentum 1 2 0.27 84,700
Holder Shares Held % O/S Shares Change Filing Date
Gilder Gagnon Howe & Co. LLC 4,379,002 13.80 392,904 12/31/2016
Versant Ventures 3,921,092 12.36 1,021,977 06/08/2016
Capital Research Global Investors 2,433,000 7.67 709,949 12/31/2016
Capital World Investors 2,433,000 7.67 709,949 12/31/2016
BlackRock Institutional Trust Company, N.A. 1,915,706 6.04 448,955 12/31/2016
The Boston Company Asset Management, LLC 1,711,976 5.40 254,935 12/31/2016
Sofinnova Partners 1,700,291 5.36 -201,200 12/31/2016
Novo A/S 1,397,718 4.40 300,000 12/31/2016
Kingdon Capital Management, L.L.C. 1,379,486 4.35 311,865 12/31/2016
The Vanguard Group, Inc. 962,842 3.03 126,285 12/31/2016
TPG Capital, L.P. 936,507 2.95 222,222 12/31/2016
Pfizer, Inc. 926,309 2.92 -760,941 12/31/2015
Wasatch Advisors, Inc. 919,035 2.90 95,544 12/31/2016
Peregrine Capital Management, Inc. 736,887 2.32 13,982 12/31/2016
Wellington Management Company, LLP 678,226 2.14 40,420 12/31/2016
Schroder Investment Management North America Inc. 590,778 1.86 259,248 12/31/2016
5AM Ventures 461,563 1.45 -1,050,513 12/31/2015
Driehaus Capital Management, LLC 449,707 1.42 -358,678 12/31/2016
State Street Global Advisors (US) 391,606 1.23 84,770 12/31/2016
Clayman (Michael D) 316,622 1.00 5,146 12/20/2016
Northern Trust Investments, Inc. 301,617 0.95 48,585 12/31/2016
RBC Capital Markets Wealth Management 258,481 0.81 148,533 12/31/2016
Alyeska Investment Group, L.P. 250,000 0.79 250,000 12/31/2016
BNY Mellon Asset Management 192,282 0.61 30,239 12/31/2016
Geode Capital Management, L.L.C. 187,039 0.59 29,397 12/31/2016
Allianz Global Investors U.S. LLC 162,687 0.51 -100,474 12/31/2016
GAM Investment Management (Switzerland) AG 130,500 0.41 0 12/31/2016
TIAA Global Asset Management 127,359 0.40 15,516 12/31/2016
JP Morgan Asset Management 116,150 0.37 -2,900 12/31/2016
American Century Investment Management, Inc. 109,761 0.35 27,499 12/31/2016
BlackRock Investment Management, LLC 99,002 0.31 3,765 12/31/2016
Charles Schwab Investment Management, Inc. 96,084 0.30 23,258 12/31/2016
Morgan Stanley & Co. LLC 90,348 0.28 72,546 12/31/2016
Wall Street Associates, LLC 84,700 0.27 -55,800 12/31/2016
Wells Fargo Advisors 82,745 0.26 11,338 12/31/2016
Baron Capital Management, Inc. 74,000 0.23 36,000 12/31/2016
Susquehanna Financial Group, LLLP 70,974 0.22 70,974 12/31/2016
Guggenheim Investments 69,759 0.22 68,986 12/31/2016
Mirae Asset Global Investments (USA) LLC 65,730 0.21 33,984 12/31/2016
Delaware Investments 63,485 0.20 129 12/31/2016
BMO Nesbitt Burns Inc. 58,267 0.18 32,892 12/31/2016
Barclays Capital Inc. 55,941 0.18 40,984 12/31/2016
California State Teachers Retirement System 55,113 0.17 6,000 12/31/2016
Bodick (Neil) 50,937 0.16 -15,000 03/17/2017
Squarepoint Ops LLC 47,033 0.15 47,033 12/31/2016
Millennium Management LLC 44,804 0.14 44,804 12/31/2016
Colella (Samuel D) 43,504 0.14 -62,276 06/21/2016
Mellon Capital Management Corporation 40,401 0.13 31,832 12/31/2016
Highbridge Capital Management, LLC 38,996 0.12 -40,227 12/31/2016
EAM Investors, LLC 36,882 0.12 36,882 12/31/2016

Ownership data is provided by Thompson Reuters, a third party service, and Flexion Therapeutics, Inc. does not maintain or provide information directly to this service.